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Deformable registration

• Problem: fusing images (from different modalities), taken at

different times in the treatment (before, during, after BT)

I) Some organs move and change shape dramatically

(sigmoid),

II) insertion of applicator changes topography, …

Approximation by rigid registration fails.

• Aim: to register each voxel correctly with the corresponding

voxel in a different image set in order to

evaluate the

received radiation dose

.

• Currently, especially for the pelvic region and breast it is

theoretically not solved how tissue voxels can move,

expand and shrink.