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“..local History”: Pre-delivered Dose

Part of Implant

d

i

j

(x) has a “History”.

Inverse Optimisation and Planning:

Topography based (TOP)

( )

(

)

( )

x

x

1

1

=

−  =

i

N

j

p i

H

i

j

i

H

i

j

i

i

D d D d

N

f

( )

(

)

( )

x

x

1

1

=

−  =

i

N

j

p

i

j

i

L

i

j

i

L

i

i

d D d D

N

f

“History”:

Pre-delivered Dose (previous Implants or ERT)

Fixed contribution of a part of the implant

(Fixed contribution form Ring + Tandem & TOP

of

additional interstitial needles)

* Using HIPO (Pi-Medical Ltd) implementation in Oncentra Prostate & Oncentra Brachy (Elekta, Nucletron B.V.)