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G. Edmundson, ‘‘Geometry based optimization for stepping source implants,’’ in Brachytherapy HDR and LDR, edited by A. A. Martinez, C. G.

Orton, and R. F. Mould ~Nucletron, Columbia, 1990

Van der Laarse and T. P. E. Prins, ‘‘Introduction to HDR brachytherapy optimisation,’’ in Brachytherapy from Radium to Optimization, edited by

R. F. Mould, J. Batterman, A. A. Martinez, and B. L. Speiser, Nucleotron International, Veenendaal, The Netherlands, 1994, pp. 331–351.

Y. Yu and M. C. Schell, ‘‘A genetic algorithm for the optimization of prostate implants,’’ Med. Phys. 23, 2085–2091, 1996

Kneschaurek P, Schiessl W and Wehrmann R Volume-based dose optimization in brachytherapy Int. J. Radiat. Oncol. Biol. Phys. 45 811–5,1999

Baltas, C. Kolotas, K. Geramani, R. F. Mould, G. Ioannidis, M. Kekchidi, and N. Zamboglou, ‘‘A conformal index COIN to evaluate implant quality

and dose specifications in brachytherapy,’’ Int. J. Radiat.Oncol., Biol., Phys. 40, 512–524 ~1998

Lahanas, M., Baltas, D., Zamboglou, N.: Anatomy-based three-dimensional dose optimization in brachytherapy using multiobjective genetic

algorithms. Med. Phys., 26, No. 9, 1904-1918, 1999.

Lahanas, M., Milickovic, N., Baltas, D., Zamboglou, N.: Application of Multiobjective Evolutionary Algorithms for Dose Optimization in

Brachytherapy. E. Zitzler et al. (Eds.): EMO 2001, LNCS 1993, 574-587, 2001

Milickovic, N., Lahanas, M., Baltas, D., Zamboglou, N.: Comparison of Evolutionary and Deterministic Multiobjective Algorithms for Dose

Optimization in Brachytherapy. E. Zitzler et al. (Eds.): EMO 2001, LNCS 1993, 167-180, 2001

Lessard, E., & Pouliot, J. (2001). Inverse planning anatomy-based dose optimization for HDRbrachytherapy of the prostate using fast simulated

annealing algorithm and dedicated objective function. Medical Physics, 25(5), 773-779.

Milickovic, N., Lahanas, M., Papagianopoulou, M., Zamboglou, N., Baltas, D.: Multiobjective anatomy-based dose optimization for HDR-

brachytherapy with constraint free deterministic algorithms. Phy.s Med. Biol., 47(13), 2263-2280, 2002

Lahanas, M., Baltas, D., Zamboglou, N.: A hybrid evolutionary algorithm for multi-objective anatomy-based optimization in high-dose-rate

brachytherapy. Phys. Med. Biol., 48, 399-415, 2003.

Lahanas, M., Baltas, D., Giannouli, S.: Global convergence analysis of fast multi-objective gradient-based dose optimization algorithms for high-

dose-rate brachytherapy. Phys. Med. Biol., 48, 599-617, 2003

Jozsef, G., Streeter, O. E., & Astrahan, M. A. (2003). The use of linear programming in optimization of HDR implant dose distributions. Medical

Physics, 30(5), 751-760.

Lahanas, M., Karouzakis, K., Giannouli, S., Mould, R.F., Baltas, D.: Inverse planning in brachytherapy from radium to high dose rate 192Iridium

afterloading. NOWOTWORY Journal of Oncology, 54 No 6, 535–546, 2004.

Karabis, A., Giannouli, S., Baltas, D.: HIPO: A hybrid inverse treatment planning optimization algorithm in HDR brachytherapy. Radiother. Oncol.,

76, Supplement 2, 29, 2005.

De Witt, K. D., Hsu, I.-C. J., Speight, J., Weinberg, V. K., Lessard, E., & Pouliot, J. (2005). 3D inverse treatment planning for the tandem and

ovoid applicator in cervical cancer. International Journal of Radiation Oncology, Biology, Physics, 63(4), 1270-1274.

Sumida, I., Shiomi, H., Yoshioka, Y., Inoue, T., Lessard, E., Hsu, I.-C. J., & Pouliot, J. (2006). Optimization of dose distribution for HDR

brachytherapy of the prostate using attraction-repulsion model. International Journal of Radiation Oncology, Biology, Physics, 64(2), 643-649.

Alterovitz, R., Lessard, E., Pouliot, J., Hsu, I.-C. J., O'Brien, J. F., & Goldberg, K. (2006). Optimization of HDR brachytherapy dose distributions

using linear programming with penalty costs. Medical Physics, 33(11), 4012-4019.

Literature I