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The Oligometastatic State
Oligometastatic state (by “arbitrary definition”): limited number of
metastases (
usually ≤ 5
), all amenable to radical local therapies
It was a proposal for a new clinical concept :
Intermediate
biologic state of restricted metastatic capacity between truly
locoregionally-confined and widely –metastatic cancer
Limited
number and organ sites of metastases
Transitional
state to dissemination (not yet achieved a widespread dissemination)
Weichselbaum & Hellmann. J Clin Oncol 1995;13
Weichselbaum & Hellmann. Nat Rev Clin Oncol 2011;8
In a 1995 JCO Editorial, clinical evidence led Hellmann and
Weichselbaum to coin the term “oligometastases”