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The Oligometastatic State
In such a state of limited disease burden (≤ 5 mts), the
eradication
of all sites
of metastatic disease with a
local therapy
(either
surgery or radiotherapy) could result in
long-term survival
or even
cure
in a subgroup of pts
This hypothesis is
based on long-term survival following
surgical
resection
of limited lung and liver metastases in some
tumors
Extracranial oligometastases are
different from intracranial
oligometastases
, which represent an
established clinical entity
where surgery, radiotherapy, radiosurgery have defined roles
supported by phase III RCT and detailed outcome analyses