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About

50%

of all patients with

NSCLC

present with

metastatic

disease at the time of

diagnosis

Platinum-based doublet

chemotherapy can improve

quality of life and extend

survival

,

but the prognosis

of

patients with metastatic NSCLC remains

extremely poor

,

with MST from 8 to 11 months

Moreover, the

predominant pattern of failure

in patients

with

localized NSCLC is distant

metastatic spread

Oligometastatic NSCLC