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Socinski M. and Bogart J, JCO 2007;25
Paradigm shifts in the management of SCLC:
significant contribution from RT
ED-SCLC:
LD-SCLC
Study
Regimen
Impact on Survival
Slotman et al.
(NEJM 2007)
Prophylactic cranial irradiation
+13.8% at 1 year
Slotman et al.
(Lancet 2015)
CT + PCI vs CT+ PCI + Thoracic RT +5% at 1 year