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NSCLC: EGFR TKD Mutations and Radiation Sensitivity
A549: wildtype
H820: in-frame deletion
mt EGFR TKR
show a radiation sensitive phenotype
delayed DSB repair
disturbed cell-cycle control
EGFR TKD wt
dE746-750 mtEGFR TKD
Das AK et al. Cancer Res 2006, 66:9601-9608