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PCR

Capecitabine/oxaliplatin pCR = 21% (10/48)

capecitabine/irinotecan pCR = 10% (5/48)

so the irinotecan arm was rejected

But long-term follow-up showed

Numerically superior survival (4-year OS: 85%

v 75%; P > .05)

The 4-year DFS 68% versus 62%.

Wong SJ et al. IJROBP 2015; 91(1):116-123