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Figure 1.

Time-to-event outcomes in SCCA - possible

outcomes for patients with SCCA following chemoradiation.

Patient 1

Time (months)

0

3

6

9 12 15

18

21 24 27 30

Patient 2

Patient 3

Patient 4

D/R/PFS event

= ? If YES which date

D/R/PFS event

= NO

D/R/PFS event

= YES

Progressed

Chemoradiation

0- 6 weeks

Follow-up –

CCR

OS event

YES if alive

NO if died

OS event

YES if alive

NO if died

Not CCR

Surgery

OS event

YES if alive

NO if died

CCR

Not CCR

OS event

YES if alive

NO if died

D/R/PFS event

= YES

No disease