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The role of
consolidative RT on bulky lesions
for advanced stage Hodgkin
disease is
controversial
.
Several studies have shown the
beneficial role of consolidative RT
in term of
PFS (but not in term of OS). However these results were obtained with
outdated
RT
(dose, fields and techniques)
and CT
(MOPP, Stanford V…) schedules.
Nowadays
consolidative
RT on bulky
lesions
is related
to the chemotherapy
regimen and to the PET status at the end of it.
Consolidative
RT
was not established, but
left to the discretion
of the treating
physicians (bulky lesions or residual disease at the end of chemotherapy), by many
recent randomized studies
that tested the effect of ABVD regimen (e.g.
RATHL study)
Role of RT in Advanced stage HL