Engert et al. Lancet 2012
Additional RT (30 Gy) given
only to patients with PET+
residual disease > 2.5 cm
Reduced-Intensity Chemotherapy and PET-guided
RT De-escalation TO REDUCE TOXICITY
PET
done after BEACOPP chemotherapy
can guide
the need for additional
RT
in
this setting.
HOWEVER:
Need for a
careful extrapolation
of this
PET-guided approach to
weaker regimens
that might need more vigorous additional
radiotherapy.
PET-guided RT
was
not assessed
in a
randomised fashion.