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CD3 infiltration - immunoscore
The ypTNM downstaging and TRG were used as
endpoints to evaluate response to pCRT
72% of the biopsies with high infiltration of CD3
+
cells responders to CRT
(complete or partial
response)
63% of the biopsies with a low infiltration of CD3
+
cells were non-responders to CRT
(
P
= 0.015).
Anitei M-G Clin Cancer Res 2014;20:1891