Jakobsen A 2012: endpoints
Endpoint
CRT
+brachytherap
y boost n=90
Standard CRT
n= 92
P value
pCR
18%
NS
R0 Resection 99%
90%
P= 0.03
Major
response TRG
1 and 2
44% (35/80)
28% (23/82)
P= 0.04