Conclusions
1. 5FU-based CRT more effective
(downsizing) than RT but no improvement
in SpS, DFS or OS
2. SCPRT = CRT in resectable cancer
3. Radio-sensitizing 5FU-based CRT with sub
therapeutic oxaliplatin ?
4. But minimal benefit for T3N0 on mets
5. Biologicals have not yet delivered
6. Immunotherapy is coming