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Comparison of the two trials of neo-adjuvant chemoth.

USA

GB

Control

CT Control

CT

Chemoth.

Cisplatin: 100 mg/m2

5FU: 1000 mg/m2 D1-5

3 cycles

Cisplatin: 80 mg/m2

5FU: 1000 mg/m2 D1-4

2 cycles

AdenoK. (%)

53

66

R0 (%)

59

62

54

60

Post-operative

mortality (%)

6

6

10

10

2-yr survival (%)

37

35

34

43

3-yr survival (%)

26

23

25

32