250 / 1851
CROSS Trial
Population: T1N1 or T2-T3-N0-1 and Tumour size between 5 and 8 cm
Oesophageal or gastro-oesophageal junction tumours
Surgery n=188
RT/CT then Surgery n=178
Carbo AUC2 and Taxol 50 mg/m2 D1, 8, 15, 22, 29
RT: 41.4 Gy / 1.8 Gy by fraction
Better tolerated than 5FU-Cisplatin (?)
Adenocarcinoma:
75% +++
N Engl J Med 2012;366:2074-84
Shapiro, Lancet Oncol 2015; 16: 1090–98