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Locally advanced oesophageal carcinomas:

Is surgery useful?

2 Randomized trials:

Stahl, JCO, 23: 2310-17, 2005

Bedenne, JCO, 25: 1160-68, 2007

Same design:

After concomitant chemo-radiotherapy

And a « good » response

Randomisation: Surg. or continuation of CT-RT