Diapositive 1

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UNACCEPTABLE MISONIDAZOLE RELATED TOXICITY

Symptom

Misonidazole

(330 pts)

Placebo

(296 pts)

Nausea

20%

13%

Skin rash

12%

3%

Neuropathy

26%

2%

DAHANCA 2: +/-misonidazole

Overgaard et al 1989