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“Genome-Forward” Trials
2 baseline frozen cores
70%+ tumor cellularity
DNA extracted
Ki67 in surgical sample
Greater that 10% = Unfavorable
Ki67 in surgical sample
Less than10% = Favorable
16 to 18 weeks of aromatase inhibition
2 baseline frozen cores
70%+ tumor cellularity
DNA extracted
BCRF, NHGRI, NCI