827 / 1851
Comparison of trials (Not Accord –
Brachtherapy)
Factor
RTOG 8704
RT + FU + MMC
(n = 146)
RTOG 9811
RT + FU + MMC
(n = 324)
Combined
RTOG 8704
9811
RT + FU + MMC
(n = 472)
ACT II
RT + FU + MMC
(n = 472)
Median age
62 (29-85)
55 (25-83)
57 (25-85)
58 (25 – 81)
RT OTT in days
Not stated
Median 49 days
(Kachnic)
Median 45 days
(range 1-158)
Median 38 days
(range 5-54)
Median Total
primary central
axis dose in Gy
Between 41.76
and 47.25Gy
55Gy
(range 9- 69Gy)
50.4Gy
(range 0 -
79.4Gy)
50.4 Gy
(range 9 – 54 Gy)
RT intensity
Not possible to
calculate
1.12
1.15 ( Range 0-
2.25)
1.29