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Effects on Survival and Neurocognitive Functions of Whole-Brain Radiotherapy
(WBRT) and Autologous Stem Cell Transplantation (ASCT) as Consolidation
Options After High-Dose Methotrexate-Based Chemoimmunotherapy in Patients
with Newly Diagnosed Primary CNS Lymphoma (PCNSL): Results of the Second
Randomization of the IELSG32 Trial
Ferreri AJM. et al. Blood; abstract book ASH 2016
0
12
24
36
48
60
Months
0,0
0,2
0,4
0,6
0,8
1,0
Probability, PFS
arm D
arm E
A
p= 0.17
0
12
24
36
48
60
Months
0,0
0,2
0,4
0,6
0,8
1,0
Probability, PFS
WBRT
ASCT
B
p= 0.62
PFS – Intention to treat
WBRT
ASCT
WBRT
ASCT
PFS – Per protocol