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A 55-year-old, otherwise healthy man (ECOG PS =

0

)

Former smoker (quit 10 years ago)

Suspicious 5-cm mass in right upper lobe (RUL) at the chest X-ray

Chest

CT scan

: 5x4-cm spiculated lesion in RUL and suspicious 1.7-cm

mediastinal lymph node (LN) at the 4R region

PET-CT

: 5-cm fluorodeoxyglucose (FDG) avid mass in RUL (mSUV 16.4),

right hilum, 4R node (SUV4)

Bronchoscopy and Endobronchial Ultrasound (EBUS):

Biopsy of lung lesion and 4R LN; both show adenocarcinoma

(CK7+, CK20-TTF1+)

CLINICAL CASE #1 – Locally advanced NSCLC