974 / 1851
Aupérin A, et al.
JCO
2010;28
Absolute
survival benefit
with
concomitant radio-chemotherapy:
•
5.7% at 3 years
•
4.5% at 5 years
Concomitant radio-chemotherapy
increased acute esophageal toxicity
(Grade 3-4) from 4% to 18% with a
relative risk of 4.9 (p < 0.001).
There was no significant difference
regarding acute pulmonary toxicity
“Concomitant” is better than “Sequential” Radio-Chemotherapy