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Interplay - Dynamic IMRT

Time scale of dynamic dose delivery (fluence pattern) comparable

to time scale of organ motion

Interplay effect

between organ motion and the

movement (or ‘sequencing’) of the

MLC

a volume element in the tumor

may not receive primary radiation

at all because it is always hidden

behind a leaf of the MLC

Seco et al. Med Phys(34) 2007