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Robust control

A prerequisite of high precision dose delivery is high precision of targeting.

If (all) involved uncertainties are not taken into account

reduced benefit

of highly conformal techniques.

Margins are a robust strategy for target coverage with a clear price (healthy

tissues irradiation) … but in some cases are not enough.

To fully exploit the potential of IMRT/PT in complex cases with

considerable organ motion, real time image guidance is necessary.

In the absence of accurate prognostic factors an adaptive approach (repeat

imaging – calculation – planning) is recommended in PT.

A plan is robust if treatment goals are met despite uncertainties in the

patient model and the plan remains acceptable over a range of likely

variations.

Optimal dose distribution

dose conformity, healthy tissue sparing and

robustness towards uncertainties.