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(in-vivo studies, Center of SOBP)

RBE for protons

Clinically, a value of 1.1 is adopted

Increased RBE potentially relevant at distal edge

RBE may lead to effective over-range of 1-2mm

(Paganetti 2002)

(in-vitro studies, Center of SOBP)

Residual range: ~25

m

m → Bragg peak position

(Paganetti 2002, mono-energ tic Protons, in-vitro)

Some protons are more equal than others