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Intra-operative electrons: ELIOT trial
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ELIOT system : single dose 21Gy intra-operative electrons
immediately post-operatively pioneered in Milan
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RCT of breast EBRT vs. ELIOT shows higher local cancer
recurrence with ELIOT
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EBRT 5 year recurrence 0.4%
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ELIOT 5 year recurrence 4.4%
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Only recommended in clinical trials with small tumours
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Veronesi et al. Lancet Oncology (2013) 14: 1269