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Volume definition: Organs at risk (OAR)
•
OAR
• Normal
tissue whose radiation sensitivity may
significantly influence treatment planning and/or
prescribed dose
•
Organisation/Functional Subunit Concept
• Serial
• Parallel
• Serial-Parallel
Schultheiss TE et al., Models in radiotherapy: volume effects. Med Phys 1983, 10(4):410-415. Withers HR et
al., Treatment volume and tissue tolerance. Int J Radiat Oncol Biol Phys 1988, 14(4):751-759.