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Challenges to be resolved in radiotherapy
Target definition
~45% volume reduction (p=0.002)
Proof of concept study
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60
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Tumour volume (cm
3
)
Patient
GTV
BTV
Hafeez et al., Characterisation of tumour boost with diffusion weighted MRI (DW-MRI) to
inform biological target volume for radical radiotherapy in muscle invasive bladder cancer
(MIBC) NCRI 2015.