868 / 1542
Model-based selection
Decision support system
P
IMPT
IMRT
ΔNTCP
criteria
fulfilled
?
YES
0%
10%
20%
30%
40%
50%
60%
70%
0 10 20 30 40 50 60 70
Mean dose superior PCM
NTCP(%)
Radiotherapy alone
Concomitant chemoradiation
0%
10%
20%
30%
40%
50%
60%
70%
0 10 20 30 40 50 60 70
Mean dose PCM superius
NTCP(%)
Dmean supraglottic = 10Gy
Dmean supraglottic = 20Gy
Dmean supraglottic = 30Gy
Dmean supraglottic = 40Gy
Dmean supraglottic = 50Gy
Dmean supraglottic = 60Gy
Dmean supraglottic = 70Gy
0%
10%
20%
30%
40%
50%
60%
70%
0 10 20 30 40 50 60 70
Mean dose superior PCM
NTCP(%)
Radiotherapyalone
Concomitant chemoradiation
0%
10%
20%
30%
40%
50%
60%
70%
0 10 20 30 40 50 60 70
Mean dose PCM superius
NTCP(%)
Dmean supraglottic = 10Gy
Dmean supraglottic = 20Gy
Dmean supraglottic = 30Gy
Dmean supraglottic = 40Gy
Dmean supraglottic = 50Gy
Dmean supraglottic = 60Gy
Dmean supraglottic = 70Gy
Courtesy of Hans Langendijk, UMC Groningen