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Innate immunity– microbiome
expression PRR modified
• Are innate immune
receptors expressed by
keratinocytes, which
release cytokines,
chemokines and AMP
• TLR2 Recognize Bacterial
Wall Constituents
PRRs
•
TLR
Toll like receptors----TLR2…..IL-10
• NOD
nucleotide oligomerization domain
• NLR
nucleotide like receptors
• CLR
c-type lectin receptors
• GRR
G-protein coupled receptors
• RIG
retinoid acid inducible gene
• RLR
retinoid I like receptors
PRR = pattern recognition receptors
PAMP = pathogen associated molecular patterns