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FOR EXPERT REVIEW PANEL USE ONLY

NOT FOR DISTRIBUTION

3

supermarket, analysed in duplicate on at least six different days, using 2 different instruments (same

model) and 2 different columns (same stationary phase and manufacturer, but different lot) by 2

different analysts.

Reproducibility (RSD

R

): --

System suitability

:

Calibration solutions of maltotriose (0.005 nmol/mL – 0.9 nmol/mL) at 11 different levels, were

prepared in triplicate all containing the laminaritriose internal standard (at 0.304 nmol/mL)

Recommendation:

The method tested has can determine the GOS content of most infant formula and adult

nutritional products within the concentrations typically used in such products.

The method is a significant improvement over current solutions for the determination of GOS in

lactose‐containing products.

I recommend to move this method to First Action.