1007 / 1068
SCC of the Anal Margin
•
5 – 10x less common than anal canal tumours
•
more often well differentiated & keratinizing
•
less often hrHPV positive
( 80% in women & 28%
in men – Frisch et al 1999 )
•
Small well differentiated tumours < 2cm can be
treated by local excision +/- adjuvant radiotherapy
•
Larger tumours that are poorly differentiated or
metastatic to inguinal lymph nodes ( 15 – 20 % of
patients ) are treated with radiotherapy or CRT