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Prognostic Factors in Anal Cancer

Tumour size

T stage

N stage

Distant Metastasis

? Histological type

( probably not ! )

? Histological grade

( probably not ! )

Presence of skin ulceration ( EORTC 22861 )

Male sex ( ACT 1, EORTC 22861 & RTOG 98-11 )

Low Haemoglobin ( ACT 1 )

HIV status ( not so important post HAART )

HPV status & p16 immunohistochemistry