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UNICANCER ACCORD 16 phase II trial

Inclusion: T2

>3cm

-T4 or N+ M0, HIV neg;

Cisplatin 80 mg/m²/d1

Cetuximab 400 mg/m², then weekly 250 mg/m²

5-FU 800/m²/d1-3

RT: 45 Gy in 25 # (IMRT preferred)

Boost

20 Gy in 10 #

2 weeks

break