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Pembrolizumab a humanized

monoclonal antibody against PD-1

25 heavily pretreated patients with PD-L1-positive

advanced SCCA

Overall response rate of 5/25 (20%)

Stable disease in a further 10/25 patients (40%)

(Ott P et al. Preliminary safety and efficacy results

from KEYNOTE-028 ESMO 2015).