Immune checkpoints
supports trials of immunotherapy (targeting
immune checkpoints
via anti CTLA4/PD1/PDL1 agents)
either in the metastatic setting
or potentially combined with chemo-radiotherapy
either in the concurrent or (neo) adjuvant setting
(Illidge 2015)
Illidge, T. Turning radiotherapy into an effective systemic anti-cancer treatment in
combination with immunotherapy. Clin Oncol (R Coll Radiol). 2015
Dec;27(12):696-9