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Polish Trial

n=312

Inclusion

(DRE)

Trans-Tasman

n=326

Inclusion

(ERUS;MRI)

5 x 5 Gy

5-FU CRT

Low

T3-4 Nany

Primary Endpoint

Sphincter Preservation

(15% difference)

T3 Nany

Primary Endpoint

Local Recurrences

(10% difference at 3y)