Polish Trial
5x5 Gy CRT
P value
Acute Tox (Grade 3-4, %)
3
18 <.001
pCR (%)
1
16 <.001
CRM + (%)
13
4 0.02
Sphincter Preservation (%)
61
58 n.s.
Local Recurrences (4y, %)
11
16 n.s.
Overall Survival (4y, %)
67
66 n.s.
Late Tox (Grade 3-4, %)
10
7
n.s.
Bujko et al., Radiother Oncol 2004
Buiko et al., Br J Surg 2006
Pietrzak et al. Radiother Oncol 2007
Med. F/U:
48 months