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Second interim analysis

after 500 pts in 5x5 Gy arms

(1998-2010)

5x5 Gy

immediate

TME

5x5 Gy

delayed

TME

Number of pts

234

228

Stockholm III Trial

ypT0 (%)

ypN0 (%)

2.1

63.7

11.8

71.5

CRM + (%)

11

9

Abdominoperineal Resection (%)

33

38

Petterssons et al., Br J Surg 2015