168 / 1068
cT1-2/3
low
5 x 5 Gy
+ 4 Gy Boost
4-8 weeks
Local
Excision
Polish prospective multicenter study: n= 64
ypT0-1: 67%; Local recurrence (2y) 12%
Bujko et al., Radiother Oncol 2013
cTx
M1
5 x 5 Gy
6 cycles of
CAPOX +
Bevacizumab
Surgery
Dutch M1-trial: n= 50
pCR 26%, radical operation/ablation of all tumor sites (R0) in 72%
Van Dijk et al., Ann Oncol 2013