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Current guidelines:
What is considered standard of care for RT?
Karin Haustermans
Department of Radiation Oncology
UZ Leuven
Incidence and risk factors
• Rare disease
– Annual incidence: 1/100 000 (USA)
– Incidence is rising over the last 25 years
• 5 year survival: +/- 60%
• Risk factors:
– HPV (in 90% of the patients)
– HIV or HSV (secondary role in disease progression)
– Immune suppression (transplant recipients)
– Cigarette smoking (persistence HPV)