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Mice hind leg arteries tolerate doses of up to 2,000
Gy delivered by spatially fractioned MPBs in a
single session without occlusion development
within 1 year, in contrast to the deleterious
consequences of comparable doses delivered by
seamless X-rays.
The permanent sequelae of microplanar irradiation
appear to be confined.
Conclusions
Boudewijn van der Sanden, Elke Bräuer-Krisch et al. “Tolerance of small arteries for high dose X-ray microplanar beams depends on smooth muscle cells of the normal media ”
International Journal of Radiation Oncology, Biology, Physics. Ms. No. ROB-D-09-01479R2
22
Courtesy of EBK