642-643 / 1152
Normal tissue sparing
Piglet cerebellum
15 months post ir.
300 Gy
- Cell death and damages observed only along the microbeam paths
- No damage in between microbeams
- No macroscopic tissular necrosis observed as in conventional therapy
Hyp: no necrosis
↔
no damage on normal brain vasculature
Laissue
et al. Proceedings of SPIE
. 4508. 2003
Dilmanian
et al. Neuro-oncol
. 2002. Vol 4. p. 26-38
Slatkin DN
et al. Med Phys
. 1992. Vol 19. p. 1395-400
24
Normal Tissue Sparing: Piglet cerebellum
Courtesy of EBK