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Beam Width 100µm, 6 hpi (hours post irradiation)

Morphology

Intact vasculature

Interrupted vessels in beampath

Conclusion: Zebrafish is a good model to study the sensitivity to MBs, clearly depending

on the developing state of the vasculature with similarities between normal tissue

vasculature and tumor vasculature.

Daniel Broennimann, Audrey Bouchet, Christoph Schneider, Marine Potez , Raphaël Serduc, Elke Bräuer-Krisch, Werner Graber, Stephan von Gunten, Jean Albert

Laissue and Valentin Djonov Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo

Scientific reports, 2016

MB irradiation of Zebrafish

Courtesy of EBK