Beam Width 100µm, 6 hpi (hours post irradiation)
Morphology
Intact vasculature
Interrupted vessels in beampath
Conclusion: Zebrafish is a good model to study the sensitivity to MBs, clearly depending
on the developing state of the vasculature with similarities between normal tissue
vasculature and tumor vasculature.
Daniel Broennimann, Audrey Bouchet, Christoph Schneider, Marine Potez , Raphaël Serduc, Elke Bräuer-Krisch, Werner Graber, Stephan von Gunten, Jean Albert
Laissue and Valentin Djonov Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo
Scientific reports, 2016
MB irradiation of Zebrafish
Courtesy of EBK