1304-1305 / 2605
Clinical trials
• Proton therapy
– Clinicaltrials.gov: 4 recruiting trials (1 RCT)
– MD-Anderson and MGH (NCT01512589)
•
PBT versus IMRT
•
Primary endpoints: PFS and ‘total toxicity burden’
•
Inclusion (n=180): heterogeneous: adenoC, SCC,
induction chemo
•
50.4 Gy (RBE)/28 radiochemotherapy ± surgery
•
Presumed closing date 4/2018
• Carbon ion therapy
– None found on ClinicalTrials.gov
– NIRS: CIR in early stage ES