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Page 3

Oliver Jäkel

Medical Physics

LET in a mixed field of radiation

For practical applications like in TP, RBE is based on LET

d

,

But in most cell experiments LET

t

is specified!

In a mixed radiation field, LET is usually defined as a dose

weighted average (LET

d

) or as a fluence weighted average (LET

t

):

The use of an averaged LET to derive RBE, or for treatment

planning is a purely empirical concept!