Rationale: modern perspectives
–
Switch in Pr philosophy
=
based on the concept:
«
Proton sparing normal tissues is unrivalled
»
–
Flexible concept
adjustable to patients’ population whether:
• Need for dose-escalation (± adults)
• Need for normal anatomy preservation (± children)
–
But still largely unproven « scientifically »
:
Through randomized control studies…