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Rationale: modern perspectives

• The « new » era : since the 2000s:

– Need to fight back in the raising competition with

IMXRT that also allows safe dose-escalation

studies

– Need to keep-up with modern « environment » of

Rtherapy: easiness, reliability (gantries, absence

fiducials), safety and reproducibility (QA, IGRT,

adaptive, in vivo dosimetry…)

– Need to be evaluated in the full context of

multimodal armamentarium…